Thermolysin Product Information

Literature # 9PIV400

Thermolysin is a thermostable metalloproteinase. The high digestion temperatures may be used as an alternative to denaturants to improve digestion of proteolytically resistant proteins. Thermolysin preferentially cleaves at the N-terminus of the hydrophobic residues leucine, phenylalanine, valine, isoleucine, alanine and methionine. This enzyme can be used alone or in combination with other proteases for protein analysis by mass spectrometry, protein structural studies and other applications.